ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet


















Draft FDA guidance on anti-infectives for children: It’s (mostly) all about PK and safety
Plazomicin EU marketing application is withdrawn: Near zero market value of newly approved antibacterials
Chemical vs. drugs (Part 2): How do you discriminate? / More on halicin
FDA Workshop: Animal models in support of narrow-spectrum agents for A. baumannii and P. aeruginosa
Reimbursing for innovative antibiotics / Encouraging updates from the AMR conference
COVID-19 and the Long-Term Trajectory of AMR Efforts: Wellcome Trust Deep Dive
FDA analysis of 40-years of antibacterial development: Dheman et al.
Public meeting on the LPAD Pathway: Post-meeting thoughts (wonkish)
Push! Pull! Push! Pull! / Highlights from Davos 2018
New pipeline analysis: Cancer projects were funded 17x more than antibacterials during 2011-2020
Plazomicin (Achaogen) financial post-mortem: #PassPASTEUR
Lessons in Discovery from Lynn Silver + Pro-con on alternatives to antibiotics
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet

The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet